| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50524450 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1893315 (CHEMBL4395236) |
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| Ki | 2.3±n/a nM |
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| Citation |  Romeo, G; Prezzavento, O; Intagliata, S; Pittalà, V; Modica, MN; Marrazzo, A; Turnaturi, R; Parenti, C; Chiechio, S; Arena, E; Campisi, A; Sposito, G; Salerno, L Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands. Eur J Med Chem174:226-235 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50524450 |
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| n/a |
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| Name | BDBM50524450 |
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| Synonyms: | CHEMBL4590308 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23ClN2O2 |
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| Mol. Mass. | 322.83 |
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| SMILES | Clc1ccc2oc(=O)n(CCCCN3CCCCCC3)c2c1 |
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| Structure | 
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