| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Tat |
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| Ligand | BDBM50210164 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1895070 (CHEMBL4397105) |
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| EC50 | 8100±n/a nM |
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| Citation |  Nguyen, W; Jacobson, J; Jarman, KE; Jousset Sabroux, H; Harty, L; McMahon, J; Lewin, SR; Purcell, DF; Sleebs, BE Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models. J Med Chem62:5148-5175 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein Tat |
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| Name: | Protein Tat |
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| Synonyms: | Human immunodeficiency virus type 1 Tat protein | TAT_HV1H2 | tat |
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| Type: | PROTEIN |
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| Mol. Mass.: | 9851.32 |
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| Organism: | Human immunodeficiency virus type 1 (isolate HXB2 group M subtype B)(HIV-1) |
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| Description: | ChEMBL_320712 |
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| Residue: | 86 |
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| Sequence: | MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAHQ
NSQTHQASLSKQPTSQPRGDPTGPKE
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| BDBM50210164 |
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| n/a |
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| Name | BDBM50210164 |
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| Synonyms: | CHEMBL2132936 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN4O2S |
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| Mol. Mass. | 456.988 |
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| SMILES | Cc1nnc2C(CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |c:14| |
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| Structure | 
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