| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steryl-sulfatase |
|---|
| Ligand | BDBM50118551 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1896408 (CHEMBL4398443) |
|---|
| IC50 | 0.047±n/a nM |
|---|
| Citation |  Saha, T; Makar, S; Swetha, R; Gutti, G; Singh, SK Estrogen signaling: An emanating therapeutic target for breast cancer treatment. Eur J Med Chem177:116-143 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Steryl-sulfatase |
|---|
| Name: | Steryl-sulfatase |
|---|
| Synonyms: | ARSC1 | ASC | Arylsulfatase C | STS | STS_HUMAN | Steroid sulfatase | Steryl-sulfate sulfohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 65503.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08842 |
|---|
| Residue: | 583 |
|---|
| Sequence: | MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLAS
GGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAK
LLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTT
GFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPL
NCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFA
GKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGS
NGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRI
IDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNG
CFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQT
LPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
|
|
|
|---|
| BDBM50118551 |
|---|
| n/a |
|---|
| Name | BDBM50118551 |
|---|
| Synonyms: | CHEMBL137392 | Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H15NO5S |
|---|
| Mol. Mass. | 297.327 |
|---|
| SMILES | CC(C)(C)c1cc(=O)c2cc(OS(N)(=O)=O)ccc2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
