| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steryl-sulfatase |
|---|
| Ligand | BDBM50525473 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1896984 (CHEMBL4399019) |
|---|
| IC50 | 0.680000±n/a nM |
|---|
| Citation |  Zaraei, SO; Abduelkarem, AR; Anbar, HS; Kobeissi, S; Mohammad, M; Ossama, A; El-Gamal, MI Sulfamates in drug design and discovery: Pre-clinical and clinical investigations. Eur J Med Chem179:257-271 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Steryl-sulfatase |
|---|
| Name: | Steryl-sulfatase |
|---|
| Synonyms: | ARSC1 | ASC | Arylsulfatase C | STS | STS_HUMAN | Steroid sulfatase | Steryl-sulfate sulfohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 65503.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08842 |
|---|
| Residue: | 583 |
|---|
| Sequence: | MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLAS
GGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAK
LLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTT
GFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPL
NCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFA
GKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGS
NGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRI
IDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNG
CFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQT
LPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
|
|
|
|---|
| BDBM50525473 |
|---|
| n/a |
|---|
| Name | BDBM50525473 |
|---|
| Synonyms: | CHEMBL4520442 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21NO5S |
|---|
| Mol. Mass. | 339.407 |
|---|
| SMILES | CCCCCCc1c(C)c2ccc(OS(N)(=O)=O)cc2oc1=O |
|---|
| Structure | 
|
|---|
Search and Browse
