| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
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| Ligand | BDBM50080525 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_195832 |
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| EC50 | 92±n/a nM |
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| Citation |  Dhar, A; Liu, S; Klucik, J; Berlin, KD; Madler, MM; Lu, S; Ivey, RT; Zacheis, D; Brown, CW; Nelson, EC; Birckbichler, PJ; Benbrook, DM Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids. J Med Chem42:3602-14 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor beta |
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| Name: | Retinoic acid receptor beta |
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| Synonyms: | HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50498.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458015 |
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| Residue: | 455 |
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| Sequence: | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
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| BDBM50080525 |
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| n/a |
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| Name | BDBM50080525 |
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| Synonyms: | 1,4,4,7-Tetramethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 4-ethoxycarbonyl-phenyl ester | CHEMBL331642 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27NO4 |
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| Mol. Mass. | 381.4648 |
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| SMILES | CCOC(=O)c1ccc(OC(=O)c2cc3c(cc2C)N(C)CCC3(C)C)cc1 |
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| Structure | 
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