| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50080894 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1693 (CHEMBL616900) |
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| IC50 | 0.800000±n/a nM |
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| Citation |  Russell, MG; Beer, MS; Stanton, JA; Sohal, B; Mortishire-Smith, RJ; Castro, JL 2,7-diazabicyclo[3.3.0]octanes as novel h5-HT receptor agonists. Bioorg Med Chem Lett9:2491-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41920.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. |
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| Residue: | 377 |
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| Sequence: | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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| BDBM50080894 |
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| n/a |
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| Name | BDBM50080894 |
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| Synonyms: | 3-[(2R,3aR,6aR)-5-(4-Fluoro-benzyl)-1-methyl-octahydro-pyrrolo[3,4-b]pyrrol-2-ylmethyl]-5-[1,2,4]triazol-4-yl-1H-indole | CHEMBL82204 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27FN6 |
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| Mol. Mass. | 430.5205 |
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| SMILES | CN1[C@@H](Cc2c[nH]c3ccc(cc23)-n2cnnc2)C[C@@H]2CN(Cc3ccc(F)cc3)C[C@H]12 |
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| Structure | 
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