| Reaction Details |
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 | Report a problem with these data |
| Target | Aminodeoxyfutalosine synthase |
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| Ligand | BDBM50526601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1900272 (CHEMBL4402387) |
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| Ki | 3100±n/a nM |
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| Citation |  Joshi, S; Fedoseyenko, D; Mahanta, N; Ducati, RG; Feng, M; Schramm, VL; Begley, TP Antibacterial Strategy against ACS Med Chem Lett10:363-366 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminodeoxyfutalosine synthase |
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| Name: | Aminodeoxyfutalosine synthase |
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| Synonyms: | 2.5.1.120 | AFL synthase | Aminodeoxyfutalosine synthase | Aminofutalosine synthase | MQNE_THET8 | Menaquinone biosynthetic enzyme MqnE | mqnE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42621.64 |
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| Organism: | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
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| Description: | ChEMBL_119077 |
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| Residue: | 372 |
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| Sequence: | MRGIRDPRLIPIAEKVMEGKRLSFEDGLVLYQTKDLPTLMRLANLVRERKHGHKTYFVHS
IRVSQTNICYVGCTFCAFQRRFGEEGAWDWDVDEVVAWVKERYQPGLTEIHLTAGHHPKR
PFAYYLDLVRALKENFPGVQVKAWTAAEIHHFSKIARLPYREVLKALKEAGLDAMPGGGA
EIFAERVRRKIARAKVSAEGWLEIHRTAHELGIPTNATMLYGHIETLEERLDHMDRLRRL
QDETGGFMSFIPLAFQPDGNQLARELGKKEFTTGLDDLRNLAVARLYLDNFPHIKGYWAT
LTPELAQVSLDWGVTDVDGTLIEERIVHMAGSPTPQGLTKRELARIILMAGRIPVERDAL
YREVRVWDRVEA
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| BDBM50526601 |
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| n/a |
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| Name | BDBM50526601 |
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| Synonyms: | CHEMBL4461488 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H10O4 |
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| Mol. Mass. | 206.1947 |
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| SMILES | OC(=O)C(=C)Cc1cccc(c1)C(O)=O |
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| Structure | 
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