| Reaction Details |
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 | Report a problem with these data |
| Target | Polyphenol oxidase 2 |
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| Ligand | BDBM50526630 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1900399 (CHEMBL4402621) |
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| Ki | 73400±n/a nM |
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| Citation |  Kim, JY; Kim, JY; Jenis, J; Li, ZP; Ban, YJ; Baiseitova, A; Park, KH Tyrosinase inhibitory study of flavonolignans from the seeds of Silybum marianum (Milk thistle). Bioorg Med Chem27:2499-2507 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyphenol oxidase 2 |
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| Name: | Polyphenol oxidase 2 |
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| Synonyms: | Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase |
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| Type: | Protein |
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| Mol. Mass.: | 63923.66 |
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| Organism: | Agaricus bisporus (Common mushroom) |
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| Description: | O42713 |
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| Residue: | 556 |
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| Sequence: | MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLP
FTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWV
QAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPY
GDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDD
QHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVW
VTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGG
TKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKK
FELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNH
YLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDH
TQARVVFDDVAVHVIN
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| BDBM50526630 |
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| n/a |
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| Name | BDBM50526630 |
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| Synonyms: | CHEMBL9353 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14O7 |
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| Mol. Mass. | 318.2782 |
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| SMILES | COc1cc(ccc1O)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O |r| |
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| Structure | 
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