| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-2 |
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| Ligand | BDBM50526813 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1901163 (CHEMBL4403385) |
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| IC50 | 81±n/a nM |
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| Citation |  Xi, J; Zhuang, R; Kong, L; He, R; Zhu, H; Zhang, J Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases. Eur J Med Chem182:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-2 |
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| Name: | Proteasome subunit beta type-2 |
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| Synonyms: | 20S proteasome | PSB2_HUMAN | PSMB2 | Proteasome Macropain subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22837.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1294233 |
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| Residue: | 201 |
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| Sequence: | MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYI
QKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDY
LAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSV
RIIDKNGIHDLDNISFPKQGS
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| BDBM50526813 |
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| n/a |
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| Name | BDBM50526813 |
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| Synonyms: | CHEMBL4465456 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H48N4O5 |
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| Mol. Mass. | 604.7794 |
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| SMILES | CC(C)C[C@H](NC(=O)CN1CCCCCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| |
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| Structure | 
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