| Reaction Details |
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 | Report a problem with these data |
| Target | Heme oxygenase 1 |
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| Ligand | BDBM50375318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1901234 (CHEMBL4403456) |
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| IC50 | 410±n/a nM |
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| Citation |  Intagliata, S; Salerno, L; Ciaffaglione, V; Leonardi, C; Fallica, AN; Carota, G; Amata, E; Marrazzo, A; Pittalą, V; Romeo, G Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors. Eur J Med Chem183:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Heme oxygenase 1 |
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| Name: | Heme oxygenase 1 |
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| Synonyms: | HMOX1_RAT | HSP32 | Heme Oxygenase 1 (HO-1) | Heme oxygenase 1 | Hmox1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 33005.15 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | HO-1 obtained from rat spleen was used in enzyme assays. |
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| Residue: | 289 |
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| Sequence: | MERPQLDSMSQDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTA
LEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHE
VGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQ
LYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTEEHKDQSPSQTEFLRQRP
ASLVQDTTSAETPRGKSQISTSSSQTPLLRWVLTLSFLLATVAVGIYAM
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| BDBM50375318 |
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| n/a |
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| Name | BDBM50375318 |
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| Synonyms: | Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TERCONAZOLE | Terazol | Terazol 3 | Terazol 7 | med.21724, Compound Terconazole |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31Cl2N5O3 |
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| Mol. Mass. | 532.462 |
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| SMILES | CC(C)N1CCN(CC1)c1ccc(OC[C@H]2CO[C@@](Cn3cncn3)(O2)c2ccc(Cl)cc2Cl)cc1 |
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| Structure | 
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