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Reaction Details
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TargetFree fatty acid receptor 3
LigandBDBM50527469
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1902654 (CHEMBL4404876)
EC50 1349±n/a nM
Citation Ulven, ERQuon, TSergeev, EBarki, NBrvar, MHudson, BDDutta, PHansen, AHBielefeldt, LŲTobin, ABMcKenzie, CJMilligan, GUlven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem63:3577-3595 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Free fatty acid receptor 3
Name:Free fatty acid receptor 3
Synonyms:FFAR3_RAT | Ffar3 | Free fatty acid receptor 3 | G-protein coupled receptor 41 | Gpr41
Type:PROTEIN
Mol. Mass.:36493.02
Organism:Rattus norvegicus
Description:ChEMBL_117217
Residue:319
Sequence:
MDTSFFPGNHWLFFSVDLLVFLVGLPLNVMALVVFVNKLRRRPVAVDLLLLNLTISDLLL
LLFLPFRIVEAACGMKWILPFIFCPLSGFLFFTTIYLTSLFLMTVSIERFLSVAYPLWYK
TRPRLAQAGLVSGICWFLASAHCSVIYVTEYWGNATYSQGTNGTCYLEFREDQLAILLPV
RLEMAVVLFMVPLCITSYCYSRLVWILSQGASRRRRKRVMGLLVATLLIFFVCFGPYNMS
HVVGYVRGESPTWRSYVLLLSTLNSCIDPLVFYFSSSKFQADFHQLLSRLIRACVPWTQE
VSLELKVKNGEEPSKECPS
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  Blast E-value cutoff:
BDBM50527469
n/a
NameBDBM50527469
Synonyms:CHEMBL4448591
TypeSmall organic molecule
Emp. Form.C22H22N2O3
Mol. Mass.362.4217
SMILESCC1=C(C(c2ccco2)C2=C(CCCC2=O)N1)C(=O)Nc1ccccc1C |t:1,10|
Structure
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