| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 3 |
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| Ligand | BDBM50527479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1902638 (CHEMBL4404860) |
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| EC50 | 3715±n/a nM |
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| Citation |  Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LŲ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem63:3577-3595 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 3 |
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| Name: | Free fatty acid receptor 3 |
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| Synonyms: | FFAR3 | FFAR3_HUMAN | GPR41 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38655.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508992 |
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| Residue: | 346 |
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| Sequence: | MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS
DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP
LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI
LLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGP
YNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQ
WQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
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| BDBM50527479 |
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| n/a |
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| Name | BDBM50527479 |
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| Synonyms: | CHEMBL4517214 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23BrN2O2 |
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| Mol. Mass. | 451.356 |
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| SMILES | CC1=C(C(C2=C(CCCC2=O)N1)c1ccc(Br)cc1)C(=O)Nc1ccccc1C |t:1,4| |
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| Structure | 
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