| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50527831 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1903817 (CHEMBL4406039) |
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| Ki | 1980±n/a nM |
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| Citation |  Tosh, DK; Salmaso, V; Rao, H; Bitant, A; Fisher, CL; Lieberman, DI; Vorbrüggen, H; Reitman, ML; Gavrilova, O; Gao, ZG; Auchampach, JA; Jacobson, KA Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A J Med Chem63:4334-4348 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20857.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q5BJF2 |
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| Residue: | 176 |
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| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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| BDBM50527831 |
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| n/a |
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| Name | BDBM50527831 |
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| Synonyms: | CHEMBL4571380 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H27N5O4 |
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| Mol. Mass. | 497.5451 |
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| SMILES | [H][C@@]12C[C@]1([H])[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCCc3ccc(O)c(OC)c3)nc(nc12)C#Cc1ccccc1 |r| |
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| Structure | 
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