| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 11 |
|---|
| Ligand | BDBM60927 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1904591 (CHEMBL4406949) |
|---|
| IC50 | >40000±n/a nM |
|---|
| Citation |  Lu, S; He, X; Ni, D; Zhang, J Allosteric Modulator Discovery: From Serendipity to Structure-Based Design. J Med Chem62:6405-6421 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mitogen-activated protein kinase 11 |
|---|
| Name: | Mitogen-activated protein kinase 11 |
|---|
| Synonyms: | MAP kinase p38 | MAPK11 | MK11_HUMAN | Mitogen-activated protein kinase 11 | Mitogen-activated protein kinase p38 beta | PRKM11 | SAPK2 | SAPK2B | Stress-activated protein kinase 2 | p38 MAP kinase alpha/beta | p38-2 | p38-beta | p38b |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41351.73 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_20128774 |
|---|
| Residue: | 364 |
|---|
| Sequence: | MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
|
|
|
|---|
| BDBM60927 |
|---|
| n/a |
|---|
| Name | BDBM60927 |
|---|
| Synonyms: | 1-anilinonaphthalene-8-sulfonic acid | 8-Anilino-1-naphthalenesulfonic acid | ANS | Anilinonaphthalene-8-sulfonic acid (ANS) | BDBM50126831 |
|---|
| Type | n/a |
|---|
| Emp. Form. | C16H13NO3S |
|---|
| Mol. Mass. | 299.344 |
|---|
| SMILES | OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
