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Target5-hydroxytryptamine receptor 7
LigandBDBM50529073
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1907304 (CHEMBL4409662)
Ki 11±n/a nM
Citation Gu, ZSWang, WTQian, HZhou, ANSun, HBZhang, QWLi, JQ Synthesis and antidepressant effect of novel aralkyl piperazine and piperidine derivatives targeting SSRI/5-HT Bioorg Med Chem Lett29:0 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 7
Name:5-hydroxytryptamine receptor 7
Synonyms:5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:53573.08
Organism:Homo sapiens (Human)
Description:P34969
Residue:479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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  Blast E-value cutoff:
BDBM50529073
n/a
NameBDBM50529073
Synonyms:CHEMBL4543789
TypeSmall organic molecule
Emp. Form.C25H25F2N3O
Mol. Mass.421.4823
SMILESFc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(c1)-c1ccoc1
Structure
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