| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-1 receptor antagonist protein |
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| Ligand | BDBM50529330 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1908435 (CHEMBL4410793) |
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| Ki | 1300±n/a nM |
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| Citation |  Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D Exploration of zinc-binding groups for the design of inhibitors for the oxytocinase subfamily of M1 aminopeptidases. Bioorg Med Chem27:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interleukin-1 receptor antagonist protein |
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| Name: | Interleukin-1 receptor antagonist protein |
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| Synonyms: | ICIL-1RA | IL-1RN | IL-1ra | IL1 inhibitor | IL1F3 | IL1RA | IL1RA_HUMAN | IL1RN | INN=Anakinra | IRAP | Interleukin-1 receptor antagonist protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 20053.78 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118941 |
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| Residue: | 177 |
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| Sequence: | MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYL
QGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
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| BDBM50529330 |
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| n/a |
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| Name | BDBM50529330 |
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| Synonyms: | CHEMBL4527760 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H35N5O4 |
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| Mol. Mass. | 541.6407 |
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| SMILES | CCCC[C@H](N)C(=O)NNc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| |
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| Structure | 
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