| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosinase |
|---|
| Ligand | BDBM50044784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1908922 (CHEMBL4411368) |
|---|
| IC50 | 30±n/a nM |
|---|
| Citation |  Pillaiyar, T; Namasivayam, V; Manickam, M; Jung, SH Inhibitors of Melanogenesis: An Updated Review. J Med Chem61:7395-7418 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosinase |
|---|
| Name: | Tyrosinase |
|---|
| Synonyms: | TYRO_MOUSE | Tyr |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 60600.74 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | n/a |
|---|
| Residue: | 533 |
|---|
| Sequence: | MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILL
SSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIR
RNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMH
YYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRD
AENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRN
PGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQS
SMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGH
NRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLG
AALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
|
|
|
|---|
| BDBM50044784 |
|---|
| n/a |
|---|
| Name | BDBM50044784 |
|---|
| Synonyms: | CHEBI:79090 | SB-202190 | US10865384, Compound SB202190 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H14FN3O |
|---|
| Mol. Mass. | 331.3431 |
|---|
| SMILES | Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
