| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50193667 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1908902 (CHEMBL4411348) |
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| IC50 | 300±n/a nM |
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| Citation |  Pillaiyar, T; Namasivayam, V; Manickam, M; Jung, SH Inhibitors of Melanogenesis: An Updated Review. J Med Chem61:7395-7418 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | TYRO_MOUSE | Tyr |
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| Type: | Protein |
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| Mol. Mass.: | 60600.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 533 |
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| Sequence: | MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILL
SSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIR
RNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMH
YYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRD
AENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRN
PGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQS
SMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGH
NRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLG
AALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
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| BDBM50193667 |
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| n/a |
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| Name | BDBM50193667 |
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| Synonyms: | 2,4,3',5'-tetrahydroxybibenzyl | CHEMBL221291 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14O4 |
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| Mol. Mass. | 246.2586 |
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| SMILES | Oc1ccc(CCc2cc(O)cc(O)c2)c(O)c1 |
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| Structure | 
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