| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50251013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1908899 (CHEMBL4411345) |
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| IC50 | 3800±n/a nM |
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| Citation |  Pillaiyar, T; Namasivayam, V; Manickam, M; Jung, SH Inhibitors of Melanogenesis: An Updated Review. J Med Chem61:7395-7418 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | TYRO_MOUSE | Tyr |
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| Type: | Protein |
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| Mol. Mass.: | 60600.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 533 |
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| Sequence: | MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILL
SSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIR
RNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMH
YYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRD
AENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRN
PGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQS
SMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGH
NRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLG
AALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
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| BDBM50251013 |
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| n/a |
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| Name | BDBM50251013 |
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| Synonyms: | 2,4,2',4'-tetrahydroxy-3'-prenylchalcone | CHEMBL465880 | morachalcone A |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20O5 |
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| Mol. Mass. | 340.3698 |
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| SMILES | [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2-[#8])c1-[#8] |
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| Structure | 
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