| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50061927 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30603 (CHEMBL642010) |
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| Ki | >10000±n/a nM |
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| Citation |  Sauer, R; Maurinsh, J; Reith, U; Fülle, F; Klotz, KN; Müller, CE Water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A(2A)-selective adenosine receptor antagonists. J Med Chem43:440-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50061927 |
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| n/a |
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| Name | BDBM50061927 |
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| Synonyms: | 8-[(E)-2-(3-Bromo-phenyl)-vinyl]-3,7-dimethyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione | 8-[2-(3-Bromo-phenyl)-vinyl]-3,7-dimethyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione(BS-DMPX) | CHEMBL136047 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15BrN4O2 |
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| Mol. Mass. | 399.241 |
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| SMILES | Cn1c(\C=C\c2cccc(Br)c2)nc2n(C)c(=O)n(CC#C)c(=O)c12 |
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| Structure | 
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