| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 22 |
|---|
| Ligand | BDBM50263036 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1914764 (CHEMBL4417347) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  McCullough, BS; Batsomboon, P; Hutchinson, KB; Dudley, GB; Barrios, AM Synthesis and PTP Inhibitory Activity of Illudalic Acid and Its Methyl Ether, with Insights into Selectivity for LAR PTP over Other Tyrosine Phosphatases under Physiologically Relevant Conditions. J Nat Prod82:3386-3393 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity protein phosphatase 22 |
|---|
| Name: | Dual specificity protein phosphatase 22 |
|---|
| Synonyms: | DUS22_HUMAN | DUSP22 | Dual specificity phosphatase 22 | Dual specificity protein phosphatase (MKPX) | Dual specificity protein phosphatase 22 | Dual specificity protein phosphatase 22 (VHX) | Dual specificity protein phosphatase VHX (VHX) | JSP1 | LMWDSP2 | MKPX | Mitogen-activated protein kinase phosphatase x | VHX |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 20915.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9NRW4 |
|---|
| Residue: | 184 |
|---|
| Sequence: | MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
LRRL
|
|
|
|---|
| BDBM50263036 |
|---|
| n/a |
|---|
| Name | BDBM50263036 |
|---|
| Synonyms: | 3-Hydroxy-6-methoxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9-hexahydro-cyclopenta[h]isochromene-5-carbaldehyde | CHEMBL518277 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18O5 |
|---|
| Mol. Mass. | 290.3111 |
|---|
| SMILES | COc1c2CC(C)(C)Cc2c2C(=O)OC(O)Cc2c1C=O |
|---|
| Structure | 
|
|---|
Search and Browse
