| Reaction Details |
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 | Report a problem with these data |
| Target | Collagenase ColA |
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| Ligand | BDBM50086781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49486 |
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| Ki | 5000±n/a nM |
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| Citation |  Scozzafava, A; Supuran, CT Protease inhibitors: synthesis of clostridium histolyticum collagenase inhibitors incorporating sulfonyl-L-alanine hydroxamate moieties. Bioorg Med Chem Lett10:499-502 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Collagenase ColA |
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| Name: | Collagenase ColA |
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| Synonyms: | 120 kDa collagenase | COLA_CLOPE | Microbial collagenase | colA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 125901.02 |
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| Organism: | Clostridium perfringens |
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| Description: | ChEMBL_49485 |
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| Residue: | 1104 |
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| Sequence: | MKKNLKRGELTKLKLVERWSATFTLAAFILFNSSFKVLAADKKVENSNNGQITREINADQ
ISKTELNNEVATDNNRPLGPSIAPSRARNNKIYTFDELNRMNYSDLVELIKTISYENVPD
LFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQL
SYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQDGVVEALGRLIGNASADPEVINNCIYVL
SDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKNTEFYNRIDPYMERLE
SLCTIGDKLNNDNAWLVNNALYYTGRMGKFREDPSISQRALERAMKEYPYLSYQYIEAAN
DLDLNFGGKNSSGNDIDFNKIKADAREKYLPKTYTFDDGKFVVKAGDKVTEEKIKRLYWA
SKEVKAQFMRVVQNDKALEEGNPDDILTVVIYNSPEEYKLNRIINGFSTDNGGIYIENIG
TFFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFF
AGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGSWDFYNYGFALSNYMYNNNMGM
FNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSLLNNIDNLDVPLVSDEYVNGH
EAKDINEITNDIKEVSNIKDLSSNVEKSQFFTTYDMRGTYVGGRSQGEENDWKDMNSKLN
DILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIK
SDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVT
DNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYY
FDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLS
VYTYDNQSGTYTVNVKGNLKNEVKETAKDAIKEVENNNDFDKAMKVDSNSKIVGTLSNDD
LKDIYSIDIQNPSDLNIVVENLDNIKMNWLLYSADDLSNYVDYANADGNKLSNTCKLNPG
KYYLCVYQFENSGTGNYIVNLQNK
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| BDBM50086781 |
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| n/a |
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| Name | BDBM50086781 |
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| Synonyms: | 2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsulfonamido)-N-hydroxypropanamide | CHEMBL123775 | N-Hydroxy-2-[(4-nitro-benzyl)-pentafluorobenzenesulfonyl-amino]-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12F5N3O6S |
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| Mol. Mass. | 469.34 |
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| SMILES | CC(N(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)NO |
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| Structure | 
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