Reaction Details |
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Target | 5-hydroxytryptamine receptor 1A |
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Ligand | BDBM50052865 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_931 (CHEMBL615779) |
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Ki | 80±n/a nM |
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Citation | Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Derivatives of (R)-1,11-methyleneaporphine: synthesis, structure, and interactions with G-protein coupled receptors. J Med Chem43:1339-49 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 1A |
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Name: | 5-hydroxytryptamine receptor 1A |
Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
Type: | n/a |
Mol. Mass.: | 46122.49 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 422 |
Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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BDBM50052865 |
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n/a |
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Name | BDBM50052865 |
Synonyms: | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | CHEMBL281357 |
Type | Small organic molecule |
Emp. Form. | C17H17N |
Mol. Mass. | 235.3236 |
SMILES | CN1CCc2cccc3-c4ccccc4C[C@@H]1c23 |
Structure |
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