| Reaction Details |
|---|
 | Report a problem with these data |
| Target | AMP deaminase 2 |
|---|
| Ligand | BDBM50087298 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_28868 (CHEMBL644200) |
|---|
| Ki | 2100±n/a nM |
|---|
| Citation |  Bookser, BC; Kasibhatla, SR; Appleman, JR; Erion, MD AMP deaminase inhibitors. 2. Initial discovery of a non-nucleotide transition-state inhibitor series. J Med Chem43:1495-507 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| AMP deaminase 2 |
|---|
| Name: | AMP deaminase 2 |
|---|
| Synonyms: | AMP deaminase 2 | AMP deaminase 2 (hAMPD2) | AMPD2 | AMPD2_HUMAN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 100694.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 879 |
|---|
| Sequence: | MRNRGQGLFRLRSRCFLHQSLPLGAGRRKGLDVAEPGPSRCRSDSPAVAAVVPAMASYPS
GSGKPKAKYPFKKRASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFPLDLRTSMD
GKCKEIAEELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLR
AKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDA
AKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPP
ALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVN
VLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIH
ASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHAD
RNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELR
LSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLP
LFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYL
YYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQ
YLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEY
SIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRV
GYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
|
|
|
|---|
| BDBM50087298 |
|---|
| n/a |
|---|
| Name | BDBM50087298 |
|---|
| Synonyms: | 6-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-phenyl-hexanoic acid 0.75H2O.0.27CH3CO2H | CHEMBL288348 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22N4O3 |
|---|
| Mol. Mass. | 342.3923 |
|---|
| SMILES | OC1CNC=Nc2c1ncn2CCCCC(C(O)=O)c1ccccc1 |c:4| |
|---|
| Structure | 
|
|---|
Search and Browse
