| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
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| Ligand | BDBM50531922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1921535 (CHEMBL4424380) |
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| IC50 | 12000±n/a nM |
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| Citation |  Lee, JW; Hirota, T; Ono, D; Honma, S; Honma, KI; Park, K; Kay, SA Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase I? and ?. J Med Chem62:1989-1998 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform delta |
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| Name: | Casein kinase I isoform delta |
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| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47356.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48730 |
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| Residue: | 415 |
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| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
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| BDBM50531922 |
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| n/a |
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| Name | BDBM50531922 |
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| Synonyms: | CHEMBL4471178 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16F3N5 |
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| Mol. Mass. | 335.3269 |
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| SMILES | CC(C)n1cnc2c(NCc3cccc(c3)C(F)(F)F)ncnc12 |
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| Structure | 
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