| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Genome polyprotein |
|---|
| Ligand | BDBM50087771 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_76921 (CHEMBL688665) |
|---|
| EC50 | 100000±n/a nM |
|---|
| Citation |  Reich, SH; Johnson, T; Wallace, MB; Kephart, SE; Fuhrman, SA; Worland, ST; Matthews, DA; Hendrickson, TF; Chan, F; Meador, J; Ferre, RA; Brown, EL; DeLisle, DM; Patick, AK; Binford, SL; Ford, CE Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation. J Med Chem43:1670-83 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Genome polyprotein |
|---|
| Name: | Genome polyprotein |
|---|
| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44361.04 |
|---|
| Organism: | Human rhinovirus B |
|---|
| Description: | ChEMBL_158953 |
|---|
| Residue: | 401 |
|---|
| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
|
|
|
|---|
| BDBM50087771 |
|---|
| n/a |
|---|
| Name | BDBM50087771 |
|---|
| Synonyms: | 3-(3-Carbamoyl-phenyl)-acrylic acid phenethyl ester | CHEMBL44323 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H17NO3 |
|---|
| Mol. Mass. | 295.3325 |
|---|
| SMILES | NC(=O)c1cccc(\C=C\C(=O)OCCc2ccccc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
