| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50087776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_76921 (CHEMBL688665) |
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| EC50 | 5600±n/a nM |
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| Citation |  Reich, SH; Johnson, T; Wallace, MB; Kephart, SE; Fuhrman, SA; Worland, ST; Matthews, DA; Hendrickson, TF; Chan, F; Meador, J; Ferre, RA; Brown, EL; DeLisle, DM; Patick, AK; Binford, SL; Ford, CE Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation. J Med Chem43:1670-83 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44361.04 |
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| Organism: | Human rhinovirus B |
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| Description: | ChEMBL_158953 |
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| Residue: | 401 |
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| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
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| BDBM50087776 |
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| n/a |
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| Name | BDBM50087776 |
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| Synonyms: | 3-[3-Carbamoyl-5-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-ylsulfanylmethyl)-phenyl]-acrylic acid ethyl ester | CHEMBL44631 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N4O4S |
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| Mol. Mass. | 410.446 |
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| SMILES | CCOC(=O)\C=C\c1cc(CSc2nnc(o2)-c2ccccn2)cc(c1)C(N)=O |
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| Structure | 
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