| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50532920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1924137 (CHEMBL4427093) |
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| IC50 | >100000±n/a nM |
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| Citation |  Neves, BJ; Dantas, RF; Senger, MR; Melo-Filho, CC; Valente, WC; de Almeida, AC; Rezende-Neto, JM; Lima, EF; Paveley, R; Furnham, N; Muratov, E; Kamentsky, L; Carpenter, AE; Braga, RC; Silva-Junior, FP; Andrade, CH Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening. J Med Chem59:7075-88 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50532920 |
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| n/a |
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| Name | BDBM50532920 |
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| Synonyms: | CHEMBL4522839 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11NO2S2 |
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| Mol. Mass. | 289.373 |
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| SMILES | O=S(=O)(Cc1ccccc1)c1nc2ccccc2s1 |
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| Structure | 
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