| Reaction Details |
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 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
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| Ligand | BDBM50534076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1927716 (CHEMBL4430788) |
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| IC50 | 1048000±n/a nM |
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| Citation |  Ziemska, J; Gu?piel, A; Jarosz, J; Nasulewicz-Goldeman, A; Wietrzyk, J; Kaw?cki, R; Pypowski, K; Jaro?czyk, M; Solecka, J Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents. Bioorg Med Chem24:5302-5314 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytosol aminopeptidase |
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| Name: | Cytosol aminopeptidase |
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| Synonyms: | 3.4.11.1 | 3.4.11.5 | 3.4.13.23 | AMPL_PIG | Cysteinylglycine-S-conjugate dipeptidase | LAP-3 | LAP3 | Leucine aminopeptidase 3 | Leucyl aminopeptidase | Proline aminopeptidase | Prolyl aminopeptidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56047.39 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_101481 |
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| Residue: | 519 |
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| Sequence: | MFLLPLPAAARVAVRQLSVRRFWGPGPDAANMTKGLVLGIYSKEKEDDAPQFTSAGENFD
KLVSGKLREILNISGPPLKAGKTRTFYGLHEDFSSVVVVGLGKKGAGVDDQENWHEGKEN
IRAAVAAGCRQIQDLEIPSVEVDPCGDAQAAAEGAVLGLYEYDELKQKKKVVVSAKLHGS
GDQEAWQRGVLFASGQNLARHLMETPANEMTPTRFAEVIEKNLKSASSKTDVHIRPKSWI
EEQEMGSFLSVAKGSEEPPVFLEIHYKGSPDASDPPLVFVGKGITFDSGGISIKASANMD
LMRADMGGAATICSTIVSAAKLDLPINLVGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDIALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTKQIVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMAGRPTRTLIEFLLRFSQDSA
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| BDBM50534076 |
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| n/a |
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| Name | BDBM50534076 |
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| Synonyms: | CHEMBL4435767 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H27NO6 |
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| Mol. Mass. | 473.5171 |
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| SMILES | COc1cc2CCC(N=Cc2cc1OC)(C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 |c:8| |
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| Structure | 
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