| Reaction Details |
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 | Report a problem with these data |
| Target | Relaxin-3 receptor 2 |
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| Ligand | BDBM50534445 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1929026 (CHEMBL4432202) |
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| Ki | 275±n/a nM |
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| Citation |  Hojo, K; Hossain, MA; Tailhades, J; Shabanpoor, F; Wong, LL; Ong-Pålsson, EE; Kastman, HE; Ma, S; Gundlach, AL; Rosengren, KJ; Wade, JD; Bathgate, RA Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling. J Med Chem59:7445-56 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Relaxin-3 receptor 2 |
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| Name: | Relaxin-3 receptor 2 |
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| Synonyms: | G-protein coupled receptor 100 | G-protein coupled receptor GPCR142 | GPCR142 | GPR100 | Insulin-like peptide INSL5 receptor | RL3R2_HUMAN | RLN3 receptor 2 | RLN3R2 | RXFP4 | Relaxin family peptide receptor 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41161.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1456194 |
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| Residue: | 374 |
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| Sequence: | MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
NSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESR
PSTLLTNLDRGTPG
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| BDBM50534445 |
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| n/a |
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| Name | BDBM50534445 |
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| Synonyms: | CHEMBL4476408 |
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| Type | Small organic molecule |
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| Emp. Form. | C116H185N35O27 |
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| Mol. Mass. | 2501.9284 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CN)C(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| |
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| Structure | 
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