| Reaction Details |
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 | Report a problem with these data |
| Target | Relaxin-3 receptor 1 |
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| Ligand | BDBM50534444 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1929024 (CHEMBL4432200) |
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| Ki | 603±n/a nM |
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| Citation |  Hojo, K; Hossain, MA; Tailhades, J; Shabanpoor, F; Wong, LL; Ong-Pålsson, EE; Kastman, HE; Ma, S; Gundlach, AL; Rosengren, KJ; Wade, JD; Bathgate, RA Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling. J Med Chem59:7445-56 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Relaxin-3 receptor 1 |
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| Name: | Relaxin-3 receptor 1 |
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| Synonyms: | G protein-coupled receptor SALPR | G-protein coupled receptor GPCR135 | GPCR135 | RL3R1_HUMAN | RLN3 receptor 1 | RLN3R1 | RXFP3 | Relaxin family peptide receptor 3 | SALPR | Somatostatin- and angiotensin-like peptide receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51139.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_818423 |
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| Residue: | 469 |
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| Sequence: | MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA
PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF
VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR
YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK
VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA
GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS
QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA
TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY
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| BDBM50534444 |
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| n/a |
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| Name | BDBM50534444 |
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| Synonyms: | CHEMBL4457624 |
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| Type | Small organic molecule |
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| Emp. Form. | C112H175N33O27 |
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| Mol. Mass. | 2415.7928 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@]1(C)CCC\C=C/CCC[C@](C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,c:89| |
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| Structure | 
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