| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein-arginine deiminase type-1 |
|---|
| Ligand | BDBM50535202 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1929982 (CHEMBL4433158) |
|---|
| IC50 | 408000±n/a nM |
|---|
| Citation |  Jamali, H; Khan, HA; Tjin, CC; Ellman, JA Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors. ACS Med Chem Lett7:847-51 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein-arginine deiminase type-1 |
|---|
| Name: | Protein-arginine deiminase type-1 |
|---|
| Synonyms: | PAD1 | PADI1 | PADI1_HUMAN | PDI1 | Peptidylarginine deiminase I | Protein-arginine deiminase type I |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 74664.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1290380 |
|---|
| Residue: | 663 |
|---|
| Sequence: | MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVK
EPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLE
VDTGRTGKVKRSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQDM
SPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEVER
QPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTLPEVTLFTDTVGFRMAPWIMTPNT
QPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEFGYIE
APHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSPPVTV
GGTEYPLGRILIGSSFPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDEFLTFV
PTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRHLQRDN
LHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNFYAEAFFPDMVNMVVLGKYLGIPK
PYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPFPFKWWN
MVP
|
|
|
|---|
| BDBM50535202 |
|---|
| n/a |
|---|
| Name | BDBM50535202 |
|---|
| Synonyms: | CHEMBL4546087 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18ClN3O |
|---|
| Mol. Mass. | 339.819 |
|---|
| SMILES | ClCC(=N)NCC#CC(=O)NCc1cccc(c1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
