| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-arginine deiminase type-2 |
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| Ligand | BDBM50535202 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1929983 (CHEMBL4433159) |
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| IC50 | 153000±n/a nM |
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| Citation |  Jamali, H; Khan, HA; Tjin, CC; Ellman, JA Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors. ACS Med Chem Lett7:847-51 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-arginine deiminase type-2 |
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| Name: | Protein-arginine deiminase type-2 |
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| Synonyms: | KIAA0994 | PAD-H19 | PAD2 | PADI2 | PADI2_HUMAN | PDI2 | Peptidylarginine deiminase II | Protein-arginine deiminase type II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 75552.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290379 |
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| Residue: | 665 |
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| Sequence: | MLRERTVRLQYGSRVEAVYVLGTYLWTDVYSAAPAGAQTFSLKHSEHVWVEVVRDGEAEE
VATNGKQRWLLSPSTTLRVTMSQASTEASSDKVTVNYYDEEGSIPIDQAGLFLTAIEISL
DVDADRDGVVEKNNPKKASWTWGPEGQGAILLVNCDRETPWLPKEDCRDEKVYSKEDLKD
MSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRRKLYHVVK
YTGGSAELLFFVEGLCFPDEGFSGLVSIHVSLLEYMAQDIPLTPIFTDTVIFRIAPWIMT
PNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYLNRGDRWIQDEIEFGYIEA
PHKGFPVVLDSPRDGNLKDFPVKELLGPDFGYVTREPLFESVTSLDSFGNLEVSPPVTVN
GKTYPLGRILIGSSFPLSGGRRMTKVVRDFLKAQQVQAPVELYSDWLTVGHVDEFMSFVP
IPGTKKFLLLMASTSACYKLFREKQKDGHGEAIMFKGLGGMSSKRITINKILSNESLVQE
NLYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDEDHRARAFFPNMVNMIVLDKDLGI
PKPFGPQVEEECCLEMHVRGLLEPLGLECTFIDDISAYHKFLGEVHCGTNVRRKPFTFKW
WHMVP
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| BDBM50535202 |
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| n/a |
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| Name | BDBM50535202 |
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| Synonyms: | CHEMBL4546087 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18ClN3O |
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| Mol. Mass. | 339.819 |
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| SMILES | ClCC(=N)NCC#CC(=O)NCc1cccc(c1)-c1ccccc1 |
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| Structure | 
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