| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50091131 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31054 (CHEMBL642125) |
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| Ki | 49.5±n/a nM |
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| Citation |  Colotta, V; Catarzi, D; Varano, F; Cecchi, L; Filacchioni, G; Martini, C; Trincavelli, L; Lucacchini, A Synthesis and structure-activity relationships of a new set of 2-arylpyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists. J Med Chem43:3118-24 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50091131 |
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| n/a |
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| Name | BDBM50091131 |
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| Synonyms: | 2-(3-Fluoro-phenyl)-2H-pyrazolo[3,4-c]quinolin-4-ylamine | CHEMBL321441 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11FN4 |
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| Mol. Mass. | 278.2837 |
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| SMILES | Nc1nc2ccccc2c2cn(nc12)-c1cccc(F)c1 |
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| Structure | 
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