Reaction Details |
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Target | 5-hydroxytryptamine receptor 4 |
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Ligand | BDBM29525 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_3568 (CHEMBL875082) |
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Ki | 0.53±n/a nM |
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Citation | Curtet, S; Soulier, JL; Zahradnik, I; Giner, M; Berque-Bestel, I; Mialet, J; Lezoualc'h, F; Donzeau-Gouge, P; Sicsic, S; Fischmeister, R; Langlois, M New arylpiperazine derivatives as antagonists of the human cloned 5-HT(4) receptor isoforms. J Med Chem43:3761-9 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 4 |
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Name: | 5-hydroxytryptamine receptor 4 |
Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4 |
Type: | Enzyme |
Mol. Mass.: | 43767.54 |
Organism: | Homo sapiens (Human) |
Description: | Q13639 |
Residue: | 388 |
Sequence: | MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
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BDBM29525 |
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n/a |
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Name | BDBM29525 |
Synonyms: | 3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 113808 | [3H]GR113808 |
Type | radiolabeled ligand |
Emp. Form. | C19H27N3O4S |
Mol. Mass. | 393.5 |
SMILES | Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 |
Structure |
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