Reaction Details |
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Target | Sigma intracellular receptor 2 |
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Ligand | BDBM50539159 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1977671 (CHEMBL4610806) |
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Ki | 63±n/a nM |
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Citation | Baumeister, S; Schepmann, D; Wünsch, B Thiophene bioisosteres of GluN2B selective NMDA receptor antagonists: Synthesis and pharmacological evaluation of [7]annuleno[b]thiophen-6-amines. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma intracellular receptor 2 |
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Name: | Sigma intracellular receptor 2 |
Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
Type: | Protein |
Mol. Mass.: | 20953.88 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q5U3Y7 |
Residue: | 176 |
Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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BDBM50539159 |
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n/a |
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Name | BDBM50539159 |
Synonyms: | CHEMBL4649725 |
Type | Small organic molecule |
Emp. Form. | C24H27NOS |
Mol. Mass. | 377.542 |
SMILES | Oc1ccc(cc1)-c1cc2CCC(CCc2s1)NCCCc1ccccc1 |
Structure |
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