| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha 3 |
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| Ligand | BDBM50539771 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1979300 (CHEMBL4612435) |
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| IC50 | 1.7±n/a nM |
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| Citation |  Rangasamy, L; Ortín, I; Zapico, JM; Coderch, C; Ramos, A; de Pascual-Teresa, B New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes. ACS Med Chem Lett11:713-719 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha 3 |
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| Name: | Casein kinase II subunit alpha 3 |
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| Synonyms: | 2.7.11.1 | CK II alpha 3 | CSK23_HUMAN | CSNK2A1P | CSNK2A3 | Casein kinase II alpha 1 polypeptide pseudogene | Casein kinase II subunit alpha 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45229.76 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_116899 |
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| Residue: | 391 |
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| Sequence: | MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYD
QLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANVMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAATGAQQ
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| BDBM50539771 |
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| n/a |
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| Name | BDBM50539771 |
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| Synonyms: | CHEMBL4649511 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25F3N4O6 |
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| Mol. Mass. | 510.463 |
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| SMILES | OC(=O)C(F)(F)F.ONC(=O)CCCCCCCNc1nc2cc(ccc2c2cnccc12)C(O)=O |
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| Structure | 
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