| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50540593 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1982303 (CHEMBL4615565) |
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| Ki | 35±n/a nM |
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| Citation |  Zampieri, D; Fortuna, S; Calabretti, A; Romano, M; Menegazzi, R; Schepmann, D; Wünsch, B; Mamolo, MG Synthesis, Cytotoxicity Evaluation, and Computational Insights of Novel 1,4-Diazepane-Based Sigma Ligands. ACS Med Chem Lett11:651-656 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20953.88 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5U3Y7 |
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| Residue: | 176 |
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| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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| BDBM50540593 |
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| n/a |
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| Name | BDBM50540593 |
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| Synonyms: | CHEMBL4640137 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27N3O |
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| Mol. Mass. | 373.4907 |
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| SMILES | Cc1ccc(CN2CCCN(CC2)C(=O)c2ccc3ccccc3n2)c(C)c1 |
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| Structure | 
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