| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
|---|
| Ligand | BDBM50540771 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1982772 (CHEMBL4616034) |
|---|
| Ki | 2673±n/a nM |
|---|
| Citation |  Amata, E; Dichiara, M; Gentile, D; Marrazzo, A; Turnaturi, R; Arena, E; La Mantia, A; Tomasello, BR; Acquaviva, R; Di Giacomo, C; Rescifina, A; Prezzavento, O Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation. ACS Med Chem Lett11:889-894 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma intracellular receptor 2 |
|---|
| Name: | Sigma intracellular receptor 2 |
|---|
| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 20857.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q5BJF2 |
|---|
| Residue: | 176 |
|---|
| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
|
|
|
|---|
| BDBM50540771 |
|---|
| n/a |
|---|
| Name | BDBM50540771 |
|---|
| Synonyms: | CHEMBL4643104 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27N3O4 |
|---|
| Mol. Mass. | 397.4675 |
|---|
| SMILES | [O-][N+](=O)OCc1ccc(cc1)C(=O)NCCN1CCC(Cc2ccccc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
