| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50099681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30935 (CHEMBL647744) |
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| Ki | 315680±n/a nM |
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| Citation |  Hakimelahi, GH; Mei, NW; Moosavi-Movahedi, AA; Davari, H; Hakimelahi, S; King, KY; Hwu, JR; Wen, YS Synthesis and biological evaluation of purine-containing butenolides. J Med Chem44:1749-57 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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| BDBM50099681 |
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| n/a |
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| Name | BDBM50099681 |
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| Synonyms: | 5-[2-(6-Amino-purin-9-yl)-ethylidene]-3,4-dimethoxy-5H-furan-2-one | CHEMBL301576 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N5O4 |
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| Mol. Mass. | 303.2734 |
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| SMILES | COC1=C(OC)\C(OC1=O)=C\Cn1cnc2c(N)ncnc12 |c:2| |
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| Structure | 
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