| Reaction Details |
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 | Report a problem with these data |
| Target | S-formylglutathione hydrolase |
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| Ligand | BDBM50543567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1989374 (CHEMBL4623109) |
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| Kd | 4.4±n/a nM |
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| Citation |  Chen, X; Yang, Y; Su, L; Cui, X; Shao, J; Liu, S; Zhao, B; Miao, J Finding the mechanism of esterase D activation by a small molecule. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| S-formylglutathione hydrolase |
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| Name: | S-formylglutathione hydrolase |
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| Synonyms: | 3.1.1.56 | 3.1.2.12 | ESD | ESTD_HUMAN | Esterase D | FGH | Methylumbelliferyl-acetate deacetylase | S-formylglutathione hydrolase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31465.46 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105460 |
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| Residue: | 282 |
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| Sequence: | MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQN
FISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRM
YSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVL
CPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFI
AACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA
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| BDBM50543567 |
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| n/a |
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| Name | BDBM50543567 |
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| Synonyms: | CHEMBL4635246 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16ClN3O |
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| Mol. Mass. | 349.814 |
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| SMILES | Oc1ccc(Cl)cc1C1=NN(C(C1)c1ccccc1)c1ccccn1 |t:9| |
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| Structure | 
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