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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bile acid receptor | ||
| Ligand | BDBM50544023 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1991215 (CHEMBL4624950) | ||
| EC50 | 1.3±n/a nM | ||
| Citation |  Masuda, A; Gohda, K; Iguchi, Y; Fujimori, K; Yamashita, Y; Oda, K; Une, M; Teno, N N Bioorg Med Chem28:0 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bile acid receptor | |||
| Name: | Bile acid receptor | ||
| Synonyms: | BAR | Bile acid receptor FXR | FXR | Farnesol receptor HRR-1 | HRR1 | NR1H4 | NR1H4_HUMAN | Nuclear receptor subfamily 1 group H member 4 | RIP14 | RXR-interacting protein 14 | Retinoid X receptor-interacting protein 14 | farnesoid x receptor | ||
| Type: | Nuclear Receptor | ||
| Mol. Mass.: | 55916.24 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q96RI1 | ||
| Residue: | 486 | ||
| Sequence: |
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| BDBM50544023 | |||
| n/a | |||
| Name | BDBM50544023 | ||
| Synonyms: | CHEMBL4639094 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C32H30Cl2FN3O4 | ||
| Mol. Mass. | 610.503 | ||
| SMILES | CCC(CC)n1c(nc2ccc(cc12)C(O)=O)-c1ccc(OCc2c(noc2C(C)C)-c2c(Cl)cccc2Cl)cc1F |(74.89,-22.95,;75.79,-24.19,;75.17,-25.59,;73.65,-25.75,;72.74,-24.51,;76.08,-26.84,;75.61,-28.3,;76.85,-29.2,;78.1,-28.3,;79.6,-28.61,;80.63,-27.46,;80.15,-26,;78.65,-25.69,;77.63,-26.83,;81.16,-24.85,;82.67,-25.16,;80.68,-23.38,;74.15,-28.78,;73.82,-30.29,;72.36,-30.76,;71.22,-29.73,;69.75,-30.21,;68.6,-29.17,;67.14,-29.65,;65.89,-28.74,;64.65,-29.65,;65.12,-31.12,;66.66,-31.12,;67.56,-32.36,;66.94,-33.77,;69.1,-32.2,;65.88,-27.2,;67.22,-26.43,;68.56,-27.2,;67.21,-24.87,;65.88,-24.11,;64.54,-24.88,;64.54,-26.43,;63.21,-27.2,;71.53,-28.23,;72.99,-27.75,;73.3,-26.24,)| | ||
| Structure | 
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