| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50101858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158311 |
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| Ki | 620±n/a nM |
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| Citation |  Maruyama, T; Asada, M; Shiraishi, T; Sakata, K; Seki, A; Yoshida, H; Shinagawa, Y; Maruyama, T; Ohuchida, S; Nakai, H; Kondo, K; Toda, M Design and synthesis of a highly selective EP4-receptor agonist. Part 2: 5-thia and 9beta-haloPG derivatives with improved stability. Bioorg Med Chem Lett11:2033-5 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_MOUSE | PGE receptor, EP2 subtype | Prostaglandin E2 | Prostaglandin E2 receptor EP2 subtype | Prostanoid EP2 receptor | Ptger2 | Ptgerep2 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40495.26 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 362 |
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| Sequence: | MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAG
SRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFF
SLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYV
QYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGS
SLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRA
LRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCG
QL
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| BDBM50101858 |
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| n/a |
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| Name | BDBM50101858 |
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| Synonyms: | 4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3-(methoxymethyl)phenyl)but-1-enyl)-5-oxocyclopentyl)ethylthio)butanoic acid | 4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3-methoxymethyl-phenyl)-but-1-enyl]-5-oxo-cyclopentyl}-ethylsulfanyl)-butyric acid | CHEMBL292964 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H32O6S |
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| Mol. Mass. | 436.562 |
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| SMILES | COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)c1 |
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| Structure | 
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