Reaction Details | |||
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Target | Sodium-dependent serotonin transporter | ||
Ligand | BDBM50102006 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_201982 | ||
Ki | 0.100000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Sodium-dependent serotonin transporter | |||
Name: | Sodium-dependent serotonin transporter | ||
Synonyms: | 5-HT Transporter | 5-HTT | 5HT transporter | 5HTT | Anandamid membrane transporter, AMT | Anandamide membrane transporter, AMT | Monoamine transporters; Norepinephrine & serotonin | SC6A4_RAT | Slc6a4 | Sodium-dependent serotonin transporter | Sodium-dependent serotonin transporter (SERT) | imipramine receptor | ||
Type: | Multi-pass membrane protein | ||
Mol. Mass.: | 70168.43 | ||
Organism: | Rattus norvegicus (rat) | ||
Description: | P31652 | ||
Residue: | 630 | ||
Sequence: |
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BDBM50102006 | |||
n/a | |||
Name | BDBM50102006 | ||
Synonyms: | 3-[4-(6-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-cyclohexyl]-1H-indole-5-carbonitrile | CHEMBL294481 | cis-3-(4-(6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)cyclohexyl)-1H-indole-5-carbonitrile | ||
Type | Small organic molecule | ||
Emp. Form. | C25H27N3O | ||
Mol. Mass. | 385.5014 | ||
SMILES | COc1ccc2CN(CCc2c1)[C@H]1CC[C@H](CC1)c1c[nH]c2ccc(cc12)C#N |r,wU:12.13,15.20,(10.58,5.27,;9.25,6.04,;7.91,5.27,;7.91,3.73,;6.57,2.97,;5.25,3.74,;3.93,2.97,;2.59,3.75,;2.59,5.28,;3.93,6.05,;5.26,5.28,;6.59,6.04,;1.26,2.98,;1.26,1.44,;-.07,.67,;-1.41,1.45,;-1.41,2.97,;-.08,3.75,;-2.74,.67,;-2.89,-.87,;-4.41,-1.2,;-5.19,.14,;-6.69,.45,;-7.18,1.91,;-6.15,3.07,;-4.64,2.76,;-4.16,1.3,;-6.63,4.53,;-7.11,5.99,)| | ||
Structure | ![]() |