| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50545793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1996598 (CHEMBL4630493) |
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| Ki | 1.8±n/a nM |
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| Citation |  Rusere, LN; Lockbaum, GJ; Henes, M; Lee, SK; Spielvogel, E; Rao, DN; Kosovrasti, K; Nalivaika, EA; Swanstrom, R; Kurt Yilmaz, N; Schiffer, CA; Ali, A Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere. J Med Chem63:8296-8313 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50545793 |
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| n/a |
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| Name | BDBM50545793 |
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| Synonyms: | CHEMBL4646603 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H41N3O8 |
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| Mol. Mass. | 595.6832 |
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| SMILES | [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC)C1CC1)Cc1ccccc1 |r| |
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| Structure | 
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