| Reaction Details |
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 | Report a problem with these data |
| Target | Membrane primary amine oxidase |
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| Ligand | BDBM50104434 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_200170 |
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| Ki | 3100±n/a nM |
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| Citation |  Conn, C; Shimmon, R; Cordaro, F; Hargraves, TL; Ibrahim, P Combinatorial synthesis of SSAO inhibitors using sonogashira coupling: SAR of aryl propargylic amines. Bioorg Med Chem Lett11:2565-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Membrane primary amine oxidase |
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| Name: | Membrane primary amine oxidase |
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| Synonyms: | AOC3_RAT | Amine oxidase, copper containing | Aoc3 | Semicarbazide-sensitive amine oxidase/ Vascular adhesion protein 1 (SSAO/VAP-1) | Vascular adhesion protein 1 (VAP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 84979.78 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | O08590 |
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| Residue: | 763 |
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| Sequence: | MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGRLSQPLHCPSVLPSVQPQTHPGQSQPF
ADLSPEELTAVMSFLIKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPP
VREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPVLTREYQDIQ
EMIFHRELPQASGLLHHCCFYKRQGHNLLKMTTAPRGLQSGDRATWFGIYYNLSGAGFYP
HPIGLELLVDHKALDPALWTIQKVFYQGRYYESLTQLEDMFEAGLVNVVLVPDNGTGGSW
SLKSSVPPGRAPPLQFHPEGPRFSVQGSQVRSSLWAFSFGLGAFSGPRIFDIRFQGERVA
YEISVQEAIALYGGNSPASMSTCYMDGSFGIGKYSTPLTRGVDCPYLATYVDWHFLLESQ
TPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVETVLVVRSVATLLNYDYVWDMVFH
SNGAIEVKFHATGYITSAFFFGAGEKFGNRVAEHTLGTVHTHNAHFKVDLDVAGLKNWAW
AEDLAFVPMNVPWQPEFQMQRLQVTRKLLETEEEAAFPLGNATPRYLYLASNHSNKWGHR
RGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIYNQNDPWTPTVDF
TDFISNETIAGEDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSP
DSIYFRKDQDVTDCEVNSLACLSQTANCVPDLPAFSHGGFTYK
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| BDBM50104434 |
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| n/a |
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| Name | BDBM50104434 |
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| Synonyms: | (3-Benzo[1,3]dioxol-5-yl-prop-2-ynyl)-dimethyl-amine | CHEMBL87281 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13NO2 |
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| Mol. Mass. | 203.2371 |
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| SMILES | CN(C)CC#Cc1ccc2OCOc2c1 |
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| Structure | 
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