| Reaction Details |
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 | Report a problem with these data |
| Target | Membrane primary amine oxidase |
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| Ligand | BDBM50016897 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200171 (CHEMBL810015) |
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| Ki | 900000±n/a nM |
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| Citation |  Conn, C; Shimmon, R; Cordaro, F; Hargraves, TL; Ibrahim, P Combinatorial synthesis of SSAO inhibitors using sonogashira coupling: SAR of aryl propargylic amines. Bioorg Med Chem Lett11:2565-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Membrane primary amine oxidase |
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| Name: | Membrane primary amine oxidase |
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| Synonyms: | AOC3_RAT | Amine oxidase, copper containing | Aoc3 | Semicarbazide-sensitive amine oxidase/ Vascular adhesion protein 1 (SSAO/VAP-1) | Vascular adhesion protein 1 (VAP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 84979.78 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | O08590 |
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| Residue: | 763 |
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| Sequence: | MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGRLSQPLHCPSVLPSVQPQTHPGQSQPF
ADLSPEELTAVMSFLIKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPP
VREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPVLTREYQDIQ
EMIFHRELPQASGLLHHCCFYKRQGHNLLKMTTAPRGLQSGDRATWFGIYYNLSGAGFYP
HPIGLELLVDHKALDPALWTIQKVFYQGRYYESLTQLEDMFEAGLVNVVLVPDNGTGGSW
SLKSSVPPGRAPPLQFHPEGPRFSVQGSQVRSSLWAFSFGLGAFSGPRIFDIRFQGERVA
YEISVQEAIALYGGNSPASMSTCYMDGSFGIGKYSTPLTRGVDCPYLATYVDWHFLLESQ
TPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVETVLVVRSVATLLNYDYVWDMVFH
SNGAIEVKFHATGYITSAFFFGAGEKFGNRVAEHTLGTVHTHNAHFKVDLDVAGLKNWAW
AEDLAFVPMNVPWQPEFQMQRLQVTRKLLETEEEAAFPLGNATPRYLYLASNHSNKWGHR
RGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIYNQNDPWTPTVDF
TDFISNETIAGEDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSP
DSIYFRKDQDVTDCEVNSLACLSQTANCVPDLPAFSHGGFTYK
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| BDBM50016897 |
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| n/a |
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| Name | BDBM50016897 |
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| Synonyms: | 2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) | 2-(2,6-dichloroanilino)-2-imidazoline | CLONIDINE | N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine | clonidine (amino form) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9Cl2N3 |
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| Mol. Mass. | 230.094 |
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| SMILES | Clc1cccc(Cl)c1\[#7]=[#6]-1\[#7]-[#6]-[#6]-[#7]-1 |
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| Structure | 
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