Reaction Details | |||
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Target | Bile salt export pump | ||
Ligand | BDBM50085045 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_2015021 (CHEMBL4668599) | ||
IC50 | 5900±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Bile salt export pump | |||
Name: | Bile salt export pump | ||
Synonyms: | ABCB11 | ABCBB_HUMAN | ATP-binding cassette sub-family B member 11 | BSEP | Bile Salt Export Pump, BSEP | Bile salt export pump | Bile salt export pump (BSEP) | ||
Type: | Protein | ||
Mol. Mass.: | 146405.49 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O95342 | ||
Residue: | 1321 | ||
Sequence: |
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BDBM50085045 | |||
n/a | |||
Name | BDBM50085045 | ||
Synonyms: | 5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy)phenyl)methyl)thiazolidine-2,4-dione | 5-(4-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy)benzyl)thiazolidine-2,4-dione | 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzy l]-thiazolidine-2,4-dione (troglitazone) | 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzyl]-thiazolidine-2,4-dione | 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzyl]-thiazolidine-2,4-dione(troglitazone) | 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzyl]-thiazolidine-2,4-dioneTroglitazone | CHEMBL408 | CI-991 | CS-045 | GR92132X | PRELAY | REZULIN | TROGLITAZONE | ||
Type | Small organic molecule | ||
Emp. Form. | C24H27NO5S | ||
Mol. Mass. | 441.54 | ||
SMILES | Cc1c(C)c2OC(C)(COc3ccc(Cc4sc(=O)[nH]c4O)cc3)CCc2c(C)c1O | ||
Structure | ![]() |