| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
|---|
| Ligand | BDBM50546413 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2015642 (CHEMBL4669220) |
|---|
| Ki | 800±n/a nM |
|---|
| Citation |  Bozó, É; Baska, F; Lövei, K; Szántó, G; Domány-Kovács, K; Kurkó, D; Szondiné Kordás, K; Szokoli, T; Bata, I New V1a receptor antagonist. Part 2. Identification and optimization of triazolobenzazepines. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V1a receptor |
|---|
| Name: | Vasopressin V1a receptor |
|---|
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
|---|
| Type: | Receptor |
|---|
| Mol. Mass.: | 46820.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P37288 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
|
|
|
|---|
| BDBM50546413 |
|---|
| n/a |
|---|
| Name | BDBM50546413 |
|---|
| Synonyms: | CHEMBL4780533 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H23ClN6 |
|---|
| Mol. Mass. | 394.901 |
|---|
| SMILES | CC1(C)Nc2cc(Cl)ccc2-n2c(nnc12)C1CCN(CC1)c1ccccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
