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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vasopressin V1a receptor | ||
| Ligand | BDBM50546426 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2015644 (CHEMBL4669222) | ||
| IC50 | 100±n/a nM | ||
| Citation |  Bozó, É; Baska, F; Lövei, K; Szántó, G; Domány-Kovács, K; Kurkó, D; Szondiné Kordás, K; Szokoli, T; Bata, I New V1a receptor antagonist. Part 2. Identification and optimization of triazolobenzazepines. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vasopressin V1a receptor | |||
| Name: | Vasopressin V1a receptor | ||
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor | ||
| Type: | Receptor | ||
| Mol. Mass.: | 46820.18 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P37288 | ||
| Residue: | 418 | ||
| Sequence: |
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| BDBM50546426 | |||
| n/a | |||
| Name | BDBM50546426 | ||
| Synonyms: | CHEMBL4745524 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H21ClN4O | ||
| Mol. Mass. | 368.86 | ||
| SMILES | Cc1cc(no1)[C@H]1CC[C@@H](CC1)c1nnc2CCc3cc(Cl)ccc3-n12 |r,wU:9.13,wD:6.6,(28.76,-42.13,;29.65,-43.38,;29.17,-44.83,;30.41,-45.74,;31.65,-44.84,;31.19,-43.38,;30.41,-47.28,;29.06,-48.05,;29.04,-49.6,;30.39,-50.38,;31.73,-49.62,;31.74,-48.06,;30.39,-51.93,;31.64,-52.84,;31.16,-54.3,;29.62,-54.3,;28.6,-55.45,;27.09,-55.14,;26.62,-53.68,;25.12,-53.37,;24.63,-51.92,;23.11,-51.62,;25.65,-50.77,;27.15,-51.08,;27.63,-52.53,;29.14,-52.84,)| | ||
| Structure | 
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